Impacts of Anti-dsDNA Antibody on In Vitro Fertilization-Embryo Transfer and Frozen-Thawed Embryo Transfer
Table 2
Comparison of COS and IVF outcomes among the three groups.
Variables
ANA+/anti-dsDNA+ group ()
ANA+/anti-dsDNA− group ()
ANA−/anti-dsDNA− group ()
value
Stimulation length (d)
11.06 ± 1.75
11.07 ± 1.70
10.80 ± 1.98
0.663
Total Gn dose (IU)
2404.17 ± 797.50
2400.24 ± 784.28
2337.06 ± 846.77
0.634
E2 level on HCG day (pg/ml)
3087.08 ± 927.41
3086.66 ± 1000.67
3183.55 ± 1086.38
0.866
Endometrial thickness on HCG day (mm)
10.50 ± 1.61
10.85 ± 1.80
10.67 ± 1.11
0.568
Number of retrieved oocytes
9.81 ± 1.19A,C
12.52 ± 3.50
12.89 ± 3.24
<0.001
Fertilization rate
51.0% (260/510) A,B,C
57.9% (624/1077)
69.0% (1076/1560)
<0.001
Number of embryo transferred
2.04 ± 0.19
2.01 ± 0.11
2.02 ± 0.29
0.779
Available embryos
4.15 ± 0.85A,B,C
5.24 ± 1.23
5.81 ± 0.91
<0.001
High-quality embryos
2.13 ± 0.34A,B,C
2.99 ± 0.83
3.36 ± 0.79
<0.001
Implantation rate
9.4% (10/106) B,C
15.0% (26/173)
25.8% (63/244)
<0.001
Clinical pregnancy rate
11.5% (6/52) A,B,C
30.2% (26/86)
47.1% (57/121)
<0.001
Early miscarriage rate
100% (6/6)
38.5% (10/26)
22.8% (13/57)
—
A,B,C was considered to be statistically significant among the three groups. was considered to be statistically significant between any two groups. versus those of the groups ANA+/anti-dsDNA+ and ANA+/anti-dsDNA−. versus those of the groups ANA+/anti-dsDNA− and ANA−/anti-dsDNA−. versus those of the groups ANA+/anti-dsDNA+ and ANA−/anti-dsDNA−.
