Clinical Study

Impacts of Anti-dsDNA Antibody on In Vitro Fertilization-Embryo Transfer and Frozen-Thawed Embryo Transfer

Table 3

Basal characteristics and HRT-FET outcomes among the three groups.

VariablesANA+/anti-dsDNA+
group
ANA+/anti-dsDNA−
group
ANA−/anti-dsDNA−
group

Patients324856
Age (yrs)30.78 ± 4.2131.42 ± 3.7932.43 ± 3.860.098
BMI20.32 ± 2.3821.15 ± 2.9821.71 ± 3.540.176
Duration of infertility (yrs)4.56 ± 1.644.38 ± 2.164.73 ± 0.920.093
bFSH (IU/l)5.94 ± 1.685.95 ± 1.235.74 ± 1.700.546
bLH (IU/l)3.98 ± 1.874.51 ± 1.723.85 ± 1.590.099
bE2 (pg/ml)36.19 ± 12.6232.65 ± 10.5736.71 ± 12.290.186
Endometrial thickness on progesterone
day (mm)
10.75 ± 1.6510.65 ± 1.4710.93 ± 1.020.482
E2 level on progesterone day (pg/ml)160.66 ± 33.42163.79 ± 29.06158.70 ± 24.570.791
Embryo transferred2.00 ± 0.252.04 ± 0.462.11 ± 0.310.382
Implantation rate (%)10.9% (7/64)B,C14.3% (14/98)28.0% (33/118)0.006
Clinical pregnancy rate (%)9.4% (3/32)A,B,C33.3% (16/48)57.1% (32/56)<0.001
Early miscarriage rate (%)100% (3/3)37.5% (6/16)21.9% (7/32)

A,B,C was considered to be statistically significant among the three groups. was considered to be statistically significant between any two groups. versus those of the groups ANA+/anti-dsDNA+ and ANA+/anti-dsDNA−. versus those of the groups ANA+/anti-dsDNA− and ANA−/anti-dsDNA−. versus those of the groups ANA+/anti-dsDNA+ and ANA−/anti-dsDNA−.