Impacts of Anti-dsDNA Antibody on In Vitro Fertilization-Embryo Transfer and Frozen-Thawed Embryo Transfer
Table 3
Basal characteristics and HRT-FET outcomes among the three groups.
Variables
ANA+/anti-dsDNA+ group
ANA+/anti-dsDNA− group
ANA−/anti-dsDNA− group
Patients
32
48
56
—
Age (yrs)
30.78 ± 4.21
31.42 ± 3.79
32.43 ± 3.86
0.098
BMI
20.32 ± 2.38
21.15 ± 2.98
21.71 ± 3.54
0.176
Duration of infertility (yrs)
4.56 ± 1.64
4.38 ± 2.16
4.73 ± 0.92
0.093
bFSH (IU/l)
5.94 ± 1.68
5.95 ± 1.23
5.74 ± 1.70
0.546
bLH (IU/l)
3.98 ± 1.87
4.51 ± 1.72
3.85 ± 1.59
0.099
bE2 (pg/ml)
36.19 ± 12.62
32.65 ± 10.57
36.71 ± 12.29
0.186
Endometrial thickness on progesterone day (mm)
10.75 ± 1.65
10.65 ± 1.47
10.93 ± 1.02
0.482
E2 level on progesterone day (pg/ml)
160.66 ± 33.42
163.79 ± 29.06
158.70 ± 24.57
0.791
Embryo transferred
2.00 ± 0.25
2.04 ± 0.46
2.11 ± 0.31
0.382
Implantation rate (%)
10.9% (7/64)B,C
14.3% (14/98)
28.0% (33/118)
0.006
Clinical pregnancy rate (%)
9.4% (3/32)A,B,C
33.3% (16/48)
57.1% (32/56)
<0.001
Early miscarriage rate (%)
100% (3/3)
37.5% (6/16)
21.9% (7/32)
—
A,B,C was considered to be statistically significant among the three groups. was considered to be statistically significant between any two groups. versus those of the groups ANA+/anti-dsDNA+ and ANA+/anti-dsDNA−. versus those of the groups ANA+/anti-dsDNA− and ANA−/anti-dsDNA−. versus those of the groups ANA+/anti-dsDNA+ and ANA−/anti-dsDNA−.