Research Article

Regulation of Leukocyte Recruitment to the Spleen and Peritoneal Cavity during Pristane-Induced Inflammation

Figure 4

Lack of TNFα delayed the recruitment of splenic neutrophils and macrophages in response to pristane treatment. (a, b) TNFα−/− mice and WT mice were injected with 300 μL (8.3 × 10−4 mol) of pristane and were then sacrificed at the indicated time points. The total number of cells and the number of each cell type were calculated. (c, d) The total number of cells or the number of each cell type in the PC was also analyzed. The difference between WT and TNFα−/− mice is shown. Data represent two independent experiments. , , and .
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