CD4+CD25highCD127low/−FoxP3+ Regulatory T Cell Subpopulations in the Bone Marrow and Peripheral Blood of Children with ALL: Brief Report
Table 1
Patient characteristics ().
Age
1–5 years = 26
6–11 years = 10
12–18 years = 6
Gender
Male = 21
Female = 21
Immunophenotype
B cell = 40
T cell = 2
Protocol of therapy
ALL IC BFM 2002: 1
ALL IC BFM 2009: 41
Risk group
SR: 5
IR: 25
HR: 12
CNS involvement
Positive: 2
Negative: 40
EFS
Relapse: 2
Death: 2 (after relapse: 0)
Live in first remission: 38
Steroid sensitivity
Good: 35
Poor: 6
BM on day 15
M1: 28
M2: 9
M3: 4
BM on day 33
M1: 38
M2: 1
M3: 2
One child died before the 8th day of the treatment, so we were not able to assess the sensitivity to steroids and the response to treatment on the 15th and 33rd days of chemotherapy.