Two-Parametric Immunological Score Development for Assessing Renal Involvement and Disease Activity in Systemic Lupus Erythematosus

Figure 4

Anti-dsDNA and anti-C1q combined odds ratios for the assessment of disease activity, lupus nephritis, and lupus nephritis activity. The dotted lines sectioning the graphs into 9 groups represent different cut-off selections including the manufacturer’s cut-off points at 27 IU/mL for anti-dsDNA and 20 units for anti-C1q antibodies and optimized cut-off points at 390 IU/mL for dsDNA and 54 units for C1q. The different sections of the graph are indicated by numbers (1–9). The x and y-axes are shown in logarithmic scale. The symbol (--) stands for odds ratios that cannot be calculated due to patients not having values within the range of the respective quadrant.