Distinct Profiles of CD163-Positive Macrophages in Idiopathic Interstitial Pneumonias

Figure 4

The results of receiver operating characteristic (ROC) curve analysis. The value of ROC-area under the curve shows 0.898 (95% confidence interval, CI, 0.783–1.000) for the diagnostic differentiation between IPF/UIP and NSIP. A cut-off level below 12.0 in total numerical density of CD163⁺ macrophages yielded a sensitivity of 90.5% (95% CI = 78.2–96.2%) and specificity of 88.2% (95% CI = 73.1–95.3%) for the diagnosis of IPF/UIP.