Identification of Cross-Protective Potential Antigens against Pathogenic Brucella spp. through Combining Pan-Genome Analysis with Reverse Vaccinology

Figure 3

Summary of the resultant proteins in each step of our vaccine candidate selection. The total number of analyzed proteins was 282051, the pan-genome analysis resulted in 1939 core proteins. Next, the SCL prediction pipeline resulted in 177 proteins. The number of potential protein candidates was 87, and finally the antigens with the top cumulative antigenicity score were 34.