|
| Protein ID (NCBI) | Length (aa) | Single-line annotation (NCBI) | Adhesion score | Cumulative score of 5 | Annotation note (by Blannotator, Pannzer, and eggNOG) | Domains (CD-search) | No. of β sheet strands | Biological functions | Reference |
|
| WP_004684144.1 | 274 | Porin family protein | 0.59 | 4.56 | Porin opacity type (Pannzer), heat-resistant agglutinin 1 (eggNOG) | LomR | 8 | Small solute transport, colonization, and adhesion | [64, 90] |
| WP_002964666.1 | 227 | OmpW family protein | 0.55 | 4.52 | OmpW family outer membrane protein (Pannzer, eggNOG), uncharacterized outer membrane protein y4mB (Blannotator) | OmpW | 8 | Stress response, small solute transport, and bacterial colonization | [64, 69, 91] |
| WP_002969562.1 | 155 | Hypothetical protein | 0.54 | 4.5 | Not determined | No domain hits | | ND | |
| WP_002966849.1 | 280 | DUF1849 domain-containing protein | 0.6 | 4.5 | ATP/GTP-binding site domain-containing protein A (Pannzer), DUF1849 domain-containing protein (eggNOG) | DUF1849 | | Uptake of organic nutrient | |
| WP_002964611.1 | 351 | DUF1176 domain-containing protein | 0.54 | 4.44 | DUF1176 domain-containing protein (eggNOG) | DUF1176 | | ND | |
| WP_004690357.1 | 284 | Porin family protein | 0.55 | 4.42 | Heat-resistant agglutinin 1 (Pannzer, eggNOG), uncharacterized protein BRA0921/BS1330_II0913 (Blannotator) | LomR | 8 | Small solute transport, colonization, and adhesion | [64, 90] |
| WP_004681227.1 | 238 | Type IV secretion system protein VirB1 | 0.66 | 4.38 | Type IV secretion system protein VirB 1 (Pannzer, Blannotator), conjugal transfer protein (eggNOG) | Lysozyme-like superfamily | | Adaptation to intracellular environment | [76, 92] |
| WP_002966226.1 | 182 | Hypothetical protein | 0.54 | 4.38 | UPF0423 protein BAB2_0840 (Blannotator), pathogen-specific membrane antigen (Pannzer), periplasmic protein (eggNOG) | Tpd
iron transport | | Iron acquisition and virulence | [93, 94] |
| WP_002963597.1 | 121 | Hypothetical protein | 0.5 | 4.37 | Membrane-bound lysozyme inhibitor of C-type lysozyme (by Blannotator, Pannzer, and eggNOG) | MliC | | Immune evasion and colonization/virulence factor | [95] |
| WP_004688070.1 | 192 | Hypothetical protein | 0.59 | 4.32 | Not determined | No domain hit | | ND | |
| WP_002966502.1 | 126 | Hypothetical protein | 0.62 | 4.32 | Outer membrane lipoprotein omp10 (by Blannotator, Pannzer, and eggNOG) | No domain hit | | Virulence | [65] |
| WP_002964322.1 | 329 | Hypothetical protein | 0.59 | 4.23 | 31 kDa transporter (Blannotator), alkanesulfonate transporter substrate-binding subunit (Pannzer), trap transporter solute receptor taxi family (eggNOG) | TRAP_TAXI | | Nutrient transport, pathogenicity, and colonization | [96] |
| WP_002971090.1 | 267 | Hypothetical protein | 0.54 | 4.22 | Outer membrane beta-barrel domain protein (Pannzer) | OM_channel superfamily | 10 | Adhesion | [64, 97] |
| WP_004691650.1 | 620 | TonB-dependent receptor | 0.53 | 4.21 | Iron compound TonB-dependent receptor (Pannzer), involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the transperiplasmic membrane protein TonB (by similarity) (eggNOG) | BtuB | | Iron acquisition and vitamin B12 transport | [93, 94, 98] |
| WP_002971481.1 | 168 | Outer membrane protein assembly factor BamE | 0.69 | 4.21 | Outer membrane protein assembly factor BamE (Pannzer), smpa omla domain-containing protein (eggNOG) | BamE | | Cell envelope biogenesis and OMP assembly | [99] |
| WP_004683739.1 | 236 | Porin family protein | 0.56 | 4.21 | Autotransporter outer membrane beta-barrel domain-containing protein fragment (Pannzer), hemin-binding protein (eggNOG) | LomR | 8 | Iron acquisition | [64, 90] |
| WP_004691134.1 | 403 | Hypothetical protein | 0.62 | 4.15 | Putative L,D-transpeptidase YafK (Blannotator), pollen allergen Poa pIX/Phl pVI (Pannzer), ErfK ybiS ycfS ynhG family protein (eggNOG) | Yafk | | Envelope biogenesis and stress response | [100] |
| WP_002965482.1 | 439 | Sugar ABC transporter substrate-binding protein | 0.55 | 4.11 | ABC-type sugar transport system periplasmic component (Pannzer), extracellular solute-binding protein family 1 (eggNOG) | PBP2_TMBP_like | | Uptake of organic nutrient and invasion/virulence | [73] |
| WP_002964333.1 | 220 | OmpA family protein | 0.56 | 4.09 | Probable lipoprotein YiaD (Blannotator), cell envelope biogenesis protein OmpA (Pannzer), OmpA motb domain protein (eggNOG) | OmpA | | Cell envelope biogenesis, adhesion, invasion/intracellular survival, and evasion of host defense | [67] |
| WP_023080793.1 | 661 | Heme transporter BhuA | 0.51 | 4.05 | Heme transporter BhuA (Blannotator, Pannzer), receptor (eggNOG) | CirA superfamily | | Iron acquisition, virulence, and association for bacterial persistence | [93, 94, 101] |
| WP_002964719.1 | 261 | Porin family protein | 0.57 | 4.04 | 31 kDa outer membrane immunogenic protein (Omp31) (by Blannotator, Pannzer, and eggNOG) | LomR | 8 | Hemin-binding proteins and virulence | [64, 102, 103] |
| WP_002966352.1 | 156 | DUF2271 domain-containing protein | 0.7 | 4.02 | Tat pathway signal protein (Pannzer), predicted periplasmic protein (DUF2271) (eggNOG) | DUF2271 | | ND | |
| WP_004690579.1 | 429 | Cell wall hydrolase | 0.51 | 4 | Cell wall hydrolase (Pannzer, eggNOG) | CwlJ | | Cell envelope biogenesis | [104] |
| WP_004683944.1 | 212 | Porin family protein | 0.62 | 3.98 | Omp 25 (Pannzer), membrane (eggNOG) | LomR | 8 | Virulence and adhesion | [64, 97, 105] |
| WP_011068938.1 | 792 | LPS-assembly protein LptD | 0.5 | 3.93 | LPS-assembly protein LptD (Pannzer), involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (by similarity) (eggNOG) | LptD | | Cell envelope biogenesis | [106] |
| WP_002967296.1 | 166 | BA14K family protein | 0.6 | 3.92 | Immunoreactive BA14K (Pannzer, eggNOG) | BA14K | | Lectin-like activity and virulence | [81, 82] |
| WP_002964622.1 | 170 | BA14K family protein | 0.58 | 3.92 | Glutelin (Pannzer), BA14K (eggNOG) | BA14K | | Lectin-like activity and virulence | [81, 82] |
| WP_004683466.1 | 213 | Membrane protein | 0.55 | 3.9 | 25 kDa outer membrane immunogenic protein Omp 25 (Blannotator, Pannzer), membrane (eggNOG) | LomR | 8 | Virulence and adhesion | [64, 97, 105] |
| WP_002963776.1 | 115 | DUF2147 | 0.6 | 3.89 | sn-Glycerol-3-phosphate ABC transporter ATP-binding protein (Pannzer), uncharacterized protein conserved in bacteria (DUF2147) (eggNOG) | COG4731 | | Nutrient transport and invasion/virulence | [73] |
| WP_004681306.1 | 367 | Iron ABC transporter substrate-binding protein | 0.51 | 3.88 | Periplasmic binding ABC transporter (Pannzer), solute-binding protein (eggNOG) | AfuA | | Iron acquisition and invasion/virulence | [73] |
| WP_002964998.1 | 177 | Hypothetical protein | 0.67 | 3.72 | Outer membrane lipoprotein omp19 (by Blannotator, Pannzer, and eggNOG) | Inh | | Protease inhibitor and alters the outer membrane properties | [65, 107] |
| WP_002964530.1 | 287 | Outer membrane protein assembly factor BamD | 0.52 | 3.69 | Outer membrane protein assembly factor BamD (Blannotator, Pannzer), part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (eggNOG) | BamD | | Cell envelope biogenesis, OMP assembly, and required for bacterial viability | [99] |
| WP_006278325.1 | 261 | Hypothetical protein | 0.5 | 3.69 | Proline-rich region: proline-rich extensin (Pannzer) | DNA_pol3_gamma3 superfamily | | ND | |
| WP_002963780.1 | 216 | Hypothetical protein | 0.7 | 3.58 | Not determined | No domain hit | | ND | |
|
