Anti-IL-22 Antibody Attenuates Acute Graft-versus-Host Disease via Increasing Foxp3⁺ T Cell through Modulation of CD11b⁺ Cell Function

Figure 1

IL-22 expression was increased in aGVHD mice. aGVHD was induced as described in Materials and Methods. Mice were sacrificed, and the serum and spleen were collected. IL-22 expression in (a) serum and (b) spleen cells was tested by ELISA. Data are shown as the mean ± SEM from five independent experiments. .

(a)

(b)