Association of Cytotoxic T Lymphocyte Antigen-4 Gene Polymorphisms with Psoriasis Vulgaris: A Case-Control Study in Turkish Population

Table 7

Haplotype distribution belongs to CTLA-4 polymorphisms among different subgroups of Pv.

(a)

Haplotype	Frequency	Late/early ratios (frequency)	Chi-square
AA	0.461	0.472, 0.400	0.529	0.467
GG	0.306	0.295, 0.367	0.612	0.434
AG	0.233	0.233, 0.263	1.364	0.243

(b)

Haplotype	Frequency	PASI < 12/PASI ≥ 12 ratios; (frequency)	Chi-square
AA	0.461	0.534, 0.407	3.288	0.069
GG	0.306	0.273, 0.331	0.793	0.373
AG	0.233	0.193, 0.263	1.364	0.243

Haplotypes were constructed in the following order: +49A>G (rs231775)/CT60A>G (rs3087243).