Immune Checkpoint Inhibitors to Treat Malignant Lymphomas

Figure 1

Interactions between activated T lymphocytes and tumor by the CTLA-4 (a) and the PD-1 pathway (b). APC: antigen-presenting cell; CTLA-4: cytotoxic T lymphocyte-associated protein 4; MHC: major histocompatibility complex; PD-1: programmed cell death 1; PD-L1: programmed cell death ligand 1; TCR: T cell receptor.

(a)

(b)