Human Leukocyte Antigen-A, B, C, DRB1, and DQB1 Allele and Haplotype Frequencies in a Subset of 237 Donors in the South African Bone Marrow Registry

Table 4

The twenty most frequent two, three, and four locus haplotype frequencies in the 237 donor subset (Full list in Table S2).

Two loci	Freq	Three loci	Freq	Four loci	Freq
B07:02g~C07:02g	0.145	C07:02g~DRB115:01~DQB106:02	0.107	B07:02g~C07:02~DRB115:01g~DQB106:02	0.108
DRB115:01~DQB106:02	0.125	B07:02g~DRB115:01~DQB106:02	0.106	B08:01g~C07:01g~DRB103:01~DQB102:01	0.067
C07:02g~DQB106:02	0.105	B07:02g~C07:02g~DQB106:02	0.101	A03:01g~B07:02g~C07:02g~DQB106:02	0.063
B07:02g~DQB106:02	0.099	B07:02g~C07:02g~DRB115:01	0.084	A03:01g~B07:02g~DRB115:01~DQB106:02	0.061
DRB103:01~DQB102:01	0.096	A03:01g~B07:02g~C07:02g	0.081	A03:01g~C07:02g~DRB115:01~DQB106:02	0.057
C07:02g~DRB115:01	0.091	B08:01g~DRB103:01~DQB102:01	0.076	A03:01g~B07:02g~C07:02g~DRB115:01	0.051
A03:01g~C07:02g	0.079	C07:01g~DRB103:01~DQB102:01	0.066	A01:01g~C07:01g~DRB103:01~DQB102:01	0.049
B08:01g~DQB102:01	0.071	B08:01g~C07:01g~DQB102:01	0.063	A01:01g~B08:01g~C07:01g~DQB102:01	0.047
DRB113:01~DQB106:03	0.071	A03:01g~C07:02g~DQB106:02	0.062	A01:01g~B08:01g~DRB103:01~DQB102:01	0.045
A03:01g~DQB106:02	0.061	A03:01g~B07:02g~DQB106:02	0.057	A01:01g~B08:01g~C07:01g~DRB103:01	0.037
B08:01g~C07:01g	0.058	B08:01g~C07:01g~DRB103:01	0.052	B15:01g~C03:03g~DRB113:01~DQB106:03	0.029
C07:01g~DQB102:01	0.053	A03:01g~DRB115:01~DQB106:02	0.051	B44:02g~C05:01g~DRB101:01~DQB105:01	0.025
DRB101:01~DQB105:01	0.051	A01:01g~B08:01g~C07:01g	0.047	A11:01g~C01:02g~DRB115:01~DQB106:02	0.025
DRB111:01~DQB103:01	0.051	A01:01g~C07:01g~DQB102:01	0.046	A03:01g~C07:02g~DRB101:01~DQB105:01	0.025
C07:01g~DRB103:01	0.049	A03:01g~C07:02g~DRB115:01	0.044	A03:01g~B07:02g~C07:02g~DQB103:01	0.023
C04:01g~DQB105:01	0.045	A01:01g~B08:01g~DQB102:01	0.043	A11:01g~B51:01g~DRB115:01~DQB106:02	0.023
DRB107:01~DQB102:02	0.044	A01:01g~DRB103:01~DQB102:01	0.042	A02:01g~B07:02g~DRB115:01~DQB106:02	0.023
B07:02g~DRB115:01	0.043	A01:01g~C07:01g~DRB103:01	0.037	B42:01~C17:01g~DRB103:02~DQB104:02	0.021
A01:01g~DQB102:01	0.042	A11:01g~DRB113:01~DQB106:03	0.037	B57:01g~C06:02g~DRB107:01~DQB103:03	0.021
B14:02~C08:02g	0.041	A24:02g~B07:02g~C07:02g	0.035	A01:01g~C06:02g~DRB107:01~DQB103:03	0.020

Freq: frequency; g: groups are expressed and null alleles with identical amino acid sequences across class I exons 2 and 3 and class II exon 2 [43].