Research Article
High-Density Lipoprotein Reduction Differentially Modulates to Classical and Nonclassical Monocyte Subpopulations in Metabolic Syndrome Patients and in LPS-Stimulated Primary Human Monocytes In Vitro
Table 2
Correlation coefficients of monocyte subpopulations with anthropometric, metabolic, and cellular parameters in patients with metabolic syndrome and controls.
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Coefficients (r) and values were calculated by Pearson’s correlation model. The correlation level was considered significant when . Significant associations are marked in italics. CM: classical monocytes; IM: intermediate monocytes; NCM: nonclassical monocytes; BMI: body mass index; WC: waist circumference; SBP: systolic blood pressure; FBG: fasting blood glucose; HOMA-IR: homeostatic model assessment of insulin resistance; HDL: high-density lipoprotein; LDL: low-density lipoprotein. Diagnosis of metabolic syndrome was performed according to the ATP III criteria, when three of five of the following factors were present: central obesity denoted by a waist circumference greater than 80 cm in women and 90 cm in men, hypertriglyceridemia (circulating triglyceride ), decreased serum values of HDL-cholesterol (serum in men and 50 mg/dL in women), blood pressure higher than 120/80 mmHg, and hyperglycemia (fasting blood ). |