Efficacy of a Recombinant Turkey Herpesvirus AI (H5) Vaccine in Preventing Transmission of Heterologous Highly Pathogenic H5N8 Clade 2.3.4.4b Challenge Virus in Commercial Broilers and Layer Pullets

Figure 1

Alignment of A/mute swan/Hungary/4999/2006 (H5N1) and A/goose/Hungary/1030/2017 (H5N8) HA amino acid sequences. Identical residues are marked by dots. The sites of antigenic relevance (abbreviation: “A”), the predicted epitopes (abbreviation: “E”), the predicted MHC epitopes by RANKPEP, and the MHCI/II epitope identified for AIV H5 are marked by shaded boxes according to published reports [23–25, 27].