Efficacy of a Recombinant Turkey Herpesvirus AI (H5) Vaccine in Preventing Transmission of Heterologous Highly Pathogenic H5N8 Clade 2.3.4.4b Challenge Virus in Commercial Broilers and Layer Pullets

Figure 4

Oronasal and cloacal shedding by broilers. AIV load of swab samples measured by qRRT-PCR is presented as log₁₀ELD₅₀/ml in the scatterplot; horizontal bars represent group mean value for each date. For calculation of mean, negative samples were given a value of 1.5 log₁₀ ELD₅₀/ml. Contact challenged groups (G1-VC and G2-SC) were comingled with the direct-challenged control group (G1-VCh and G2-SCh) from 8 hours postchallenge. Sampling date refers to the time after direct challenge.