Polysaccharides from Chinese Herbal Lycium barbarum Induced Systemic and Local Immune Responses in H22 Tumor-Bearing Mice

Figure 5

LBP treatment inhibited the expression of PD-1 on T-cell subsets. The PD-1 expression on T cells in tumor tissue and spleen was analyzed by FCM. (a) PD-1 expression on T cells, CD4⁺ CD25⁻ T cells and CD8⁺ T cells in tumor tissue. (b) PD-1 expression on CD4⁺ CD25⁻ T cells and CD8⁺ T cells in the spleen. PD-1 expression on T cell subsets was statistical analysis as the percentage and MFI, simultaneously. Data are represented as mean ± SD, in each group. and versus model group. PD-1: programmed cell death-1; FCM: flow cytometry; MFI: mean fluorescence intensity.

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