Immunotherapy with Native Molecule rather than Hypoallergenic Variant of Pru p 3, the Major Peach Allergen, Shows Beneficial Effects in Mice

Figure 6

SCIT with Pru p 3 or R/A Pru p 3 suppressed cytokine production in allergen-specific CD4⁺ T-cells. Splenocytes from the mice were cultured in the presence of Pru p 3 for 72 hours. The concentrations of (a) IL-13, (b) IL-4, (c) IL-10, and (d) IFN-γ in the culture supernatants were measured by ELISA.

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