The Imbalance between Foxp3+Tregs and Th1/Th17/Th22 Cells in Patients with Newly Diagnosed Autoimmune Hepatitis
Table 1
The demographic and clinical characteristics of subjects.
Parameters
AIH
HC
Number
32
20
Age (years)
48 (37–76)
51 (41–74)
Gender: female/male
24/8
14/6
ALT (U/L)
125.9 ± 108.3
27.2 ± 8.2
AST (U/L)
101.1 ± 53.7
22.7 ± 5.7
γ-GT (U/L)
89.1 ± 30.3
25.1 ± 7.4
ALP (U/L)
133.4 ± 37.1
89.5 ± 23.6
Anti-ANA (+)
23/32 (71.8%)
0/20 (0%)
Anti-ANA titer
1 : 640 (1 : 80–1 : 10000)
—
Anti-SMA (+)
2/30 (6.25%)
0/20 (0%)
Anti-SMA titer
1 : 1000 (1 : 160–1 : 3200)
—
IgG (g/L)
15.9 ± 3.7
7.8 ± 2.3
IgM (g/L)
6.9 ± 1.9
2.64 ± 0.87
IgA (g/L)
4.07 ± 2.3
1.6 ± 1.1
WBC (×109/L)
7.93 (5.6–11.2)
5.08 (3.9–9.2)
Data shown are the real case number or . Normal values: ALT: <40 IU/L; AST: <40 IU/L. Normal values: ANA: <1 : 80; SNA: <1 : 80. IgG (normal range: 7–16 g/L); IgM (normal range: 0.7–4.6 g/L); and IgA (normal range: 0.4–2.3 g/L). HC: healthy control; AIH: autoimmune hepatitis. versus HC.
