March1 E3 Ubiquitin Ligase Modulates Features of Allergic Asthma in an Ovalbumin-Induced Mouse Model of Lung Inflammation

Figure 4

March1 deficiency is associated with less IL-13, IL-10, and IL-6 in lungs of OVA-sensitized and challenged mice. IL-13 (a), IL-4 (b), IL-10 (c), IL-6 (d), and TNF-α (e) cytokines were measured in lung homogenates using an enhanced sensitivity cytometric bead array (CBA). , , (trend), N.S.: nonsignificant. Data are pooled from several independent experiments and presented in median with interquartile values (a, b, d) or in mean with SEM (c, e); –7 (a, b), –12 (c, d, e).

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