Gene Expression Profiling in Behcet’s Disease Indicates an Autoimmune Component in the Pathogenesis of the Disease and Opens New Avenues for Targeted Therapy

Figure 2

Pathways enrichment of BD modulated genes. (a) Graphical representation of genes ascribed to the enriched pathways, expressed in -axis as percentage of all genes represented on the Affymetrix Human gene chip U133A 2.0 (dark purple bars) or as the percentage of genes in the dataset of Behcet’s modulated genes (light purple bars); -axis: enriched pathways. (b) values associated with the significantly enriched pathways. Pathways with values < 0.05 versus the distribution of all genes on the microarray chip, after a Bonferroni correction, were considered as significantly enriched.

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