Research Article
Distinct Changes of BTLA and HVEM Expressions in Circulating CD4+ and CD8+ T Cells in Hepatocellular Carcinoma Patients
Table 1
Demographical and clinical characteristics.
| | Characteristics | Cases for Figures 1–3 | Cases for Figure 4 | | Patients | HD | Patients | HD |
| | Number | 25 | 18 | 12 | 8 | | Age, years (median, range) | 48, 35–69 | 40, 25–52 | 45, 35–50 | 46, 40–55 | | Gender (male/female) | 23/2 | 17/1 | 12/0 | 8/0 | | HBsAg (negative/positive) | 1/24 | 18/0 | 0/12 | 8/0 | | Cirrhosis (absent/present) | 7/18 | — | 3/9 | — | | ALT, U/L (median, range) | 34, 16–81 | — | 39, 20–76 | — | | AFP, ng/mL (≤25/>25) | 7/18 | — | 4/8 | — | | Tumor size, cm (≤5/>5) | 15/22 | — | 15/22 | — | | Tumor multiplicity (solitary/multiple) | 22/3 | — | 10/2 | — | | Vascular invasion (absent/present) | 22/3 | — | 12/0 | — | | Intrahepatic metastasis (no/yes) | 24/1 | — | 12/0 | — | | TNM stage (I + II/III + IV) | 19/6 | — | 10/2 | — | | Tumor differentiation (I + II/III + IV) | 18/7 | — | 9/3 | — | | Fibrous capsule (absent/present) | 5/20 | — | 2/10 | — |
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Abbreviations: HD: healthy donors; HBsAg: hepatitis B surface antigen; ALT: alanine aminotransferase; AFP: α-fetoprotein; TNM: tumor node metastasis.
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