Research Article
Integrin α9 Suppresses Hepatocellular Carcinoma Metastasis by Rho GTPase Signaling
Figure 4
ITGA9 suppresses HCC cell motility in vitro and in vivo. (a and b) Transwell migration and invasion assays in ITGA9-overexpressed or control HCC cells. Quantification of 6 randomly selected fields in each assay. Original magnification: 200x. (c) In vivo orthotopic metastases of ITGA9-overexpressed versus control HCC cells. Black arrows indicate metastases. (d) H&E staining of the mouse liver tissues. Scale bars, 100 μm. Data are obtained from three representative experiments. Values are means ± SEM. , , and .
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