Integrin <i>α</i>9 Suppresses Hepatocellular Carcinoma Metastasis by Rho GTPase Signaling

<div>ITGA9 affects focal adhesions and Rho GTPase activity. (a and b) Immunofluorescence staining of paxillin (red) and vinculin (red). F-Actin was stained by FITC phalloidin (green), and the cell nuclei were stained by DAPI (blue). Scale bars, 10 <i>μ</i>m. (c) Pull-down assays of the activities of RhoA, Cdc42, and Rac1 in ITGA9-overexpressed or control HCC cells. (d) FAK and Src phosphorylation of ITGA9-overexpressed versus control HCC cells. Tubulin was used as an internal control. 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Journal of Immunology Research

fig5

Figure 5

Figure 5: Integrin <i>α</i>9 Suppresses Hepatocellular Carcinoma Metastasis by Rho GTPase Signaling 

Journal of Immunology Research

Integrin α9 Suppresses Hepatocellular Carcinoma Metastasis by Rho GTPase Signaling

Figure 5