Melittin Constrains the Expression of Identified Key Genes Associated with Bladder Cancer

Figure 5

PPI network constructed by Cytoscape and top seven module networks by MCODE. (a) The PPI network was constructed dependent on the STRING online database (available online: http://string-db.org) and Cytoscape software (version 3.4.0, available online: http://www.cytoscape.org/). (b) The top seven module networks with a score no less than 4 were analyzed by MCODE. The red nodes stand for upregulated genes, and the green nodes stand for downregulated genes. The larger the node diameter is, the smaller the value and the more significant the node is. PPI: protein–protein interaction; MCODE: Molecular Complex Detection; STRING: Search Tool for the Retrieval of Interacting Genes.

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