Research Article

Carbamazepine-Mediated Adverse Drug Reactions: CBZ-10,11-epoxide but Not Carbamazepine Induces the Alteration of Peptides Presented by HLA-B15:02

Table 1

Multiple reaction monitoring (MRM) transitions monitored (m/z) with cone and collision energy.

AnalyteMRM (m/z)Dwell (s)Cone (V)Collision energy (eV)

Carbamazepine237.1 ⟶ 194.10.033913
237.1 ⟶ 179.00.033935
Carbamazepine-D8245.1 ⟶ 202.10.033222
245.1 ⟶ 185.00.033236
Carbamazepine-10,11-epoxide253.0 ⟶ 236.00.032011
253.0 ⟶ 231.20.032027
Carbamazepine-10,11-epoxide-D8261.0 ⟶ 244.10.032012
261.0 ⟶ 188.10.032022