Journal of Immunology Research

Review Article

Lung Interstitial Macrophages: Past, Present, and Future

Table 1

Expression of the indicated surface markers between alveolar macrophages (AM), interstitial macrophages (IM), CD11b+ and CD103+ conventional dendritic cells (cDCs), and Ly6C+ and Ly6C− monocytes (Mo) in the mouse lung at steady state.
MarkerAMIMCD11b+ cDCs
(cDC2)		CD103+ cDCs
(cDC1)		Ly6C+ MoLy6C− Mo
CCR2− [26, 31]+/− [26, 31]− [31]− [31]+ [26, 31]+/− [26]
CD103− [29]− [29]− [29]+ [29]− [29]− [29]
CD115+/− [26, 31]+/− [26, 31]+ [31]− [31]+ [26, 31]+ [26]
CD11b− [10, 26, 29, 31, 50]+ [10, 26, 29, 31, 50]+ [29, 50]− [29, 31]+ [26, 29, 31]+ [26, 29]
CD11c+ [10, 26, 29, 31, 32, 50]− [10, 32]; +/− [26, 31, 50]; + [29]+ [10, 29, 31, 32]+ [10, 29, 31, 32]− [26, 29]; +/− [31]+/− [26, 29]
CD14+/− [29]+ [29]+/− [29]− [29]− [29]− [29]
CD169− [13]; + [26, 31]+/− [13, 31]; + [26, 31]− [31]− [31]− [26, 31]− [26]
CD206+ [29]+/− [29]+/− [29]− [29, 31]− [29, 31]− [29]
CD24− [29]− [29]+ [29]+ [29]− [29]− [29]
CD36+ [29, 31]+ [29, 31]− [31]; +/− [29]+ [29, 31]+/− [29]; + [31]− [29]
CD64+ [26, 29, 31]+ [26, 29, 31]− [29, 31]− [29, 31]− [26]; +/− [29, 31]− [26]; +/− [29]
CD86− [50]; +/− [26]+ [26, 50]− [50] − [26]− [26]
CX3CR1− [26, 31]+ [26, 31]+/− [31]− [31]+/− [31]; + [26]+ [26]
F4/80+ [10, 26, 29, 31, 32, 50]+ [10, 26, 29, 31, 32, 50]− [10, 32, 50]; +/− [29]− [10, 29, 31, 32]+/− [31]; + [26, 29]+ [26, 29]
Ly6C− [26, 29]− [26, 29]+/− [29]− [29]+ [26, 29]− [26, 29]
Lyve-1− [31]+/− [31]− [31]− [31]− [31] 
Mertk+ [26, 31]+ [26, 31]− [31]− [31]− [26, 31]− [26]
MHC-II+/− [13, 26, 29, 32]+/− [31]; + [13, 26, 29, 32, 50]+ [29, 31, 32, 50]+ [26, 29, 31]− [26, 29]; +/− [31]− [26, 29]
SiglecF+ [26, 29, 31]− [26, 29, 31]− [29, 31]− [29, 31]− [26, 29]− [26, 29]
Zbtb46− [31]− [31]+ [31]+ [31]− [31] 
−: absence of expression or low expression; +/−: intermediate or variable expression; +: high expression.