Recent Advances in Drug-Induced Hypersensitivity Syndrome/Drug Reaction with Eosinophilia and Systemic Symptoms

Table 2

Specific human leucocyte antigen (HLA) types and associated drugs in severe drug eruptions.

Associated drug	HLA allele	Ethnicity
Abacavir	B57:01	Caucasian, Thai, Cambodian
Allopurinol	B58:01	Han Chinese, Thai, Japanese, Korean
Carbamazepine	B15:02	Han Chinese, Thai, Indian, Malaysian
	B15:11	Japanese, Korean, Han Chinese
	B59:01	Japanese
	A31:01	Japanese, Han Chinese, European, Korean
Cold medicine	A02:06	Japanese, Korean
Dapsone	B13:01	Han Chinese, Thai
Methazolamide	B59:01	Korean, Japanese, Han Chinese
Nevirapine	DRB101:01	Australian, French
	B14:02 (or Cw08:02)	European
	B35:05	Thai
	Cw08:01/Cw08:02	Sardinian, Japanese
Phenobarbital	HLA-A01:01	Thai
	HLA-B13:01	Thai
Phenytoin	B15:02	Han Chinese, Thai
	HLA-B13:01	Thai
	HLA-B56:02/04	Thai
Sulfamethoxazole	B38	European

This table is modified from [46].