A Granulocyte-Specific Protein S100A12 as a Potential Prognostic Factor Affecting Aggressiveness of Therapy in Patients with Juvenile Idiopathic Arthritis

Table 1

General characteristics of the study group.

	1^st time point ()	2^nd time point ()
Female, (%)	54 (67.5%)	36 (67.9%)
Age at diagnosis (years)	7.75 ± 4.27	7.57 ± 4.41
Age at evaluation (years)	10.40 ± 4.38	10.28 ± 4.58
Reason of admission, (%)
Fresh diagnosis of JIA	16 (20.0%)	—
Disease flare	26 (32.5%)	11 (20.8%)
Continuation of biological treatment	9 (11.25%)	12 (22.6%)
Check-up visit	29 (36.25%)	30 (56.6%)
JIA subtypes, (%)
Oligoarticular JIA	54 (67.5%)	35 (66.0%)
RF-negative polyarticular JIA	11 (13.75%)	9 (17.0%)
RF-positive polyarticular JIA	1 (1.25%)	1 (1.9%)
ERA	14 (17.5%)	8 (15.1%)
Clinical and laboratory features
Fever on admission, (%)	9 (11.3%)	0 (0.0%)
CRP > 5 mg/l, (%)	13 (16.3%)	6 (11.3%)
ESR > 20 mm/h, (%)	16 (20.0%)	4 (7.5%)
Disease activity level (according to JADAS27), (%)
Clinically inactive disease	19 (23.75%)	16 (30.2%)
Minimal disease activity	7 (8.75%)	12 (22.65%)
Parent-acceptable symptom state	5 (6.25%)	6 (11.3%)
High disease activity	49 (61.25%)	19 (35.85%)

JIA: juvenile idiopathic arthritis; RF: rheumatoid factor; ERA: enthesitis-related arthritis; JADAS27: juvenile arthritis disease activity score 27-joint reduced count.