Acer palmatum thumb. Ethanol Extract Alleviates Interleukin-6-Induced Barrier Dysfunction and Dextran Sodium Sulfate-Induced Colitis by Improving Intestinal Barrier Function and Reducing Inflammation

Figure 3

Effects of KIOM-2015E on body weight, colon length, and myeloperoxidase (MPO) activity in the dextran sodium sulfate- (DSS-) induced colitis model. (a) Body weight. (b and c) Colon length. (d) Myeloperoxidase (MPO) activity. Mice were orally administered KIOM-2015E or 5-aminosalicylic acid (5-ASA) (100 mg/kg) before DSS treatment. The body weights were monitored before KIOM-2015E or 5-ASA treatment during the experimental periods. The colonic lengths of mice were measured after being isolated from the sacrificed mice. The MPO activity was measured using MPO activity assay kit according to the manufacturer’s protocol. The results represent the mean ± standard error of the mean values of each mouse in the same group. versus the control group; and versus the DSS-treated group.

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