Research Article

Prostaglandin E2 Inhibits Prostate Cancer Progression by Countervailing Tumor Microenvironment-Induced Impairment of Dendritic Cell Migration through LXRα/CCR7 Pathway

Figure 1

PGE2 downregulates LXRα expression and activation. The maturing DCs were cultured in the conditioned medium from RM-1. The decrease in ABCG1 and ABCA1 as well as LXRα expression by PGE2 was detected by Western blot.