Influence of Biological Therapeutics, Cytokines, and Disease Activity on Depression in Rheumatoid Arthritis

Table 4

Correlations between depressive symptoms and clinical assessments in RA subjects.

	()	Pseudo	AICc	Coefficient	Odds ratio (95% CI)	value
Characteristics
Disease duration (years), mean ± SD	17.56 ± 11.48	0.252	461.64	−0.040	0.96 (0.88–1.05)	0.401
BMI, mean ± SD	26.46 ± 5.49	0.144	557.56	0.028	1.03 (1.01–1.04)	< 0.001
Pain score, median	6	0.411	527.31	0.114	1.12 (1.08–1.16)	< 0.001
Smoking, number (%)	0 (0)	< 0.001	570.11	−0.029	0.97 (0.77–1.22)	0.806
Drinking, number (%)	13 (16)	0.014	569.01	−0.129	0.88 (0.69–1.11)	0.290
Physical activity, number (%)	13 (16)	0.256	546.22	−0.668	0.51 (0.38–0.68)	< 0.001
Biologic medication, number (%)	42 (51)	0.027	570.09	−0.082	0.92 (0.73–1.18)	0.503
Classic medication, number (%)	55 (67)	0.030	569.89	−0.062	0.94 (0.75–1.19)	0.601
Disease activity (patient), mean ± SD	54.04 ± 30.16	0.880	426.21	0.002	1.01 (1.01–1.02)	< 0.001
Disease activity (doctor), mean ± SD	35.44 ± 27.03	0.890	419.81	0.013	1.01 (1.01–1.02)	< 0.001
Laboratory
Sedementation velocity, mean ± SD	26.59 ± 22.27	0.834	448.13	0.010	1.01 (1.01–1.01)	< 0.001
C-reactive protein, mean ± SD	11.11 ± 17.43	0.778	468.09	0.006	1.01 (1.00-1.01)	0.007
DAS28, mean ± SD	5.04 ± 5.65	0.830	449.81	0.038	1.04 (1.02–1.05)	< 0.001
Brain leukocytes, mean ± SD	8.09 ± 3.40	0.707	484.34	0.010	1.01 (0.98–1.04)	0.425
Brain lymphocytes, mean ± SD	27.10 ± 9.84	0.713	482.76	−0.007	0.99 (0.98–1.00)	0.139
Anti-dsDNA, mean ± SD	10.66 ± 5.30	0.999	248.28	0.017	1.02 (1.00-1.04)	0.069