Immunological Mechanisms in Allergic Diseases and Allergen Tolerance: The Role of Treg Cells

Figure 1

Main roles proposed to Tregs. Regulatory T cells could mediate the healthy immune response through different modes of action. They are able to suppress the inflammatory dendritic cells (DCs), inhibit the activation of effector T cells (Th1, Th2, Th22, and Th17) and type 2 innate lymphoid cells (ILC-2), block the secretion of inflammatory antibodies by antigen-specific B cells, and inhibit the activation of basophils, mast cells, and eosinophils.