miR-125a Suppresses TrxR1 Expression and Is Involved in H₂O₂-Induced Oxidative Stress in Endothelial Cells

Figure 3

H₂O₂ regulates TrxR1 and miR-125a expression in HUVECs. (a) Real-time and immunoblot analysis of TrxR1 in HUVECs treated with H₂O₂ (0, 0.1, 0.25, and 0.5 mmol/L). . (b) Real-time and immunoblot analysis of TrxR1 in HUVECs treated with 0.25 mmol/L H₂O₂ (0, 2, 6, 12, and 24 h). . (c) The expression of mature miR-125a in H₂O₂-treated HUVECs (0.25 mmol/L) and the control group as determined by real-time PCR. .

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