A Novel Bimodal Imaging Agent Targeting HER2 Molecule of Breast Cancer

Figure 5

The tumor-specific targeting of IR783-NBs-Affibody towards HER2 (+)/(−) breast cancer cells. (a, c)The targeting rate of NBs, NBs-Affibody, and IR783-NBs-Affibody for HER2 (+) breast cancer cells (BT-474) and HER2 (−) breast cancer cells (MDA-MB-231) via flow cytometry. (b, d) LSCM pictures of BT-474 and MDA-MB-231 cells coincubated with NBs, NBs-Affibody, and IR783-NBs-Affibody with a ×20 objective lens.

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