Altered NKp30, NKp46, NKG2D, and DNAM-1 Expression on Circulating NK Cells Is Associated with Tumor Progression in Human Gastric Cancer

<div>Galunisertib reversed TGF-<i>β</i>1-dependent downregulation of NKp30, NKp46, NKG2D, and DNAM-1 expression on NK cells. Purified NK cells from healthy donors were treated with 5 <i>μ</i>M TGF-<i>β</i> receptor I inhibitor galunisertib (G) for 1 hour followed by 10 ng/ml rhTGF-<i>β</i>1 stimulation. 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Journal of Immunology Research

fig4

Figure 4

Figure 4: Altered NKp30, NKp46, NKG2D, and DNAM-1 Expression on Circulating NK Cells Is Associated with Tumor Progression in Human Gastric Cancer 