Research Article
Differential Gene Expression Profile of Human Neutrophils Cultured with Plasmodium falciparum-Parasitized Erythrocytes
Table 2
Enriched pathways for the upregulated genes in PMNs phagocytizing iRBCs.
| Pathway | Count | value | Genes |
| Mitogen-activated protein kinase (hsa04010) | 8 | 0.000442 | HCAR1, RPS6KA2, PEBP4, RIT2, MAPK8IP2, MLLT10, CDK5RAP1, HAS1 | Insulin receptor (hsa04910) | 4 | 0.000793 | LETM1, CISH, RIT2, SOCS3 | Jak-STAT signaling pathway (hsa04630) | 5 | 0.000731 | BATF2, CISH, SOCS3, MLLT10, CXCL10 | Interleukin signaling pathway (P00970) | 4 | 0.00139 | IL1A, IL15RA, NOS3, RPS6KA2 | Interferon-gamma signaling pathway (P00035) | 2 | 0.02225 | SOCS3, CISH |
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