Immunoinformatics Approach for Epitope-Based Peptide Vaccine Design and Active Site Prediction against Polyprotein of Emerging Oropouche Virus

Figure 3

Docking simulation study (sample). (a) The docking results as the surface structure of the MHC-I HLA allele “HLA-B35:01” (tint light pink color) and the sticky form of epitope “TSSWGCEEY” (orange olive color). The black color box represents the position of epitope in the surface structure. (b) Epitope in the cartoon structure. (c) Sticky form of epitope “TSSWGCEEY” (orange olive color) with residue’s position. (d) Binding interaction of the epitope residues and the HLA-B35:01 residues through the hydrogen bonds. Hydrogen bonds and the distances are shown in green color. (e) The docking results as the surface structure of the MHC-I HLA allele “HLA-B35:01” (tint light blue color) and the sticky form of epitope “LAIDTGCLY” (orange olive color). The black color box represents the position of epitope in the surface structure. (f) Epitope LAIDTGCLY in the cartoon structure. (g) Sticky form of epitope “LAIDTGCLY” (orange olive color) with residue’s position. (h) Binding interaction of the epitope residues and the HLA-B35:01 residues through the hydrogen bonds. Hydrogen bonds and the distances are shown in green color.