Immunoinformatics Approach for Epitope-Based Peptide Vaccine Design and Active Site Prediction against Polyprotein of Emerging Oropouche Virus

Table 3

Linear B-cell epitopes of the polyprotein of OROV predicted by BepiPred-2.0.

B-cell epitopes	Position	Antigenicity score	Conservancy (%)	Toxicity	Allergenicity
					AllerTOP 2.0	AllergenFP 1.0
HPLSTSQIGDRC	17–28	1.2943	94.44	No	No	No
FKEMNLSVGL	35–44	1.9084	100.00	No	Yes	Yes
FSKNTLALEA	62–71	0.4645	5.56	No	Yes	No
VKDWSECNPVLDKL	81–94	−0.0129	5.56	No	No	No
SCTEALKVHRMGKDCLGYKS	282–301	0.4510	100.00	No	Yes	No
AGERMYKLEELADD	334–347	0.2927	38.89	No	Yes	No
IHYRPGLKVDLTK	404–416	0.4322	33.33	No	Yes	No
FDEQQSSGFEYEVFLKDMHIQRESCKFGPR	427–456	0.6740	5.56	No	Yes	Yes
DCLSKNIKITYQELH	484–498	1.2448	11.11	No	Yes	No
YIMGDTCVSKSELYSDLLSKNLITEYDKKYFEPDTVN	504–540	0.1143	5.56	No	No	No
ECEMLSLKKNSGPYN	566–580	0.6930	100.00	No	Yes	No
LCSRHNY	594–600	1.2777	100.00	No	Yes	Yes
HSMCKNTDIDFNNEIETYYKANAAAY	610–635	0.7190	5.56	No	Yes	No
NISLGRSTRSAQHSIMTNEIPKSNPFTDYSYSSVNIKECMSP	699–740	0.6399	5.56	No	Yes	Yes
KKRDSVPHT	747–755	0.9721	11.11	No	No	Yes
KYKAFDWPEIETVQKGQKLCL	765–785	1.3196	33.33	No	Yes	No
SHCNLEFTAITADKIMSL	788–805	1.0518	83.33	No	No	No
NCYKESFTAQPADMQTGI	807–824	0.8661	61.11	No	No	No
CITLEDKA	835–842	2.5070	5.56	No	No	Yes
KYYYSDGKEHAKDGSIN	851–867	0.6483	33.33	No	No	No
CSEQRFPIHKNWFKKCNWDKTHKEFTTMRQINYNDITSYRKAIES	875–919	0.1740	27.78	No	No	No
GTDLMTHHYKPTKNLPHVVPRYH	922–944	0.3102	72.22	No	No	No
AQYQKVYTTGPSISINIEHNEK	999–1020	0.6311	33.33	No	Yes	No
PEKIPAKEGWLTFSKEHTSSW	1026–1046	0.5512	100.00	No	No	No
ETYCNDMDILEPIIGD	1095–1110	0.1167	100.00	No	No	Yes
TQTNQLP	1119–1125	0.9980	100.00	No	Yes	Yes
TGQINDVGNTALQCGSIQVVNGSTIGSGNPK	1137–1167	0.8145	33.33	No	Yes	Yes
FNDNYQSCT	1186–1194	0.0858	100.00	No	No	Yes
DARNDLIPYRKG	1197–1208	1.4056	5.56	No	No	No
DINYKIFTKSV	1231–1241	0.3093	55.56	No	No	No
TVKPYNQKIDLSQLDESNYIKEEDLQCG	1322–1349	0.8134	38.89	No	No	No