Immunoinformatics Approach for Epitope-Based Peptide Vaccine Design and Active Site Prediction against Polyprotein of Emerging Oropouche Virus

Table 4

Linear B-cell epitopes of the polyprotein of OROV predicted by LBtope.

B-cell epitopes	Position	Antigenicity scores	Conservancy (%)	Toxicity	Allergenicity
					AllerTOP 2.0	AllergenFP 1.0
IAYGHPLSTSQI	13–24	0.3474	50.00	No	Yes	No
TTAFSKNTLALEAT	59–72	0.6595	5.56	No	Yes	No
PRMYTCRAACDI	110–121	−0.5422	5.56	No	Yes	No
GLKVDLTKTN	409–418	0.5124	33.33	No	Yes	Yes
SSGFEYEVFLKDMH	432–445	0.1548	38.89	No	No	No
QRESCKFGPRVNHFRNTK	447–464	1.1279	38.89	No	No	No
DLLSKNLITEYDKKYFEPDTVNDQFNKIEFAQD	519–551	0.2055	33.33	No	No	No
DFNNEIETYYKANAAAYRSDFYTI	619–642	0.1701	5.56	No	Yes	No
TRSAQHSIMTN	706–716	0.1229	38.89	No	Yes	No
HTNHLLCKMDNKYKAFDWPEIETVQK	754–779	1.0858	16.67	No	Yes	No
CITLEDKAWP	835–844	2.0270	5.56	No	No	Yes
CGDKYYYSDGKEHAKDGS	848–865	0.3358	33.33	No	Yes	No
KCNWDKT	889–895	0.4951	100.00	Yes	Yes	No
HHYKPTKNLPHVVPRYH	928–944	0.6022	100.00	No	No	No
VYTTGPSIS	1004–1013	0.4965	38.89	No	Yes	Yes
CITLPHETYCNDMDILEPII	1089–1108	0.2420	100.00	No	Yes	Yes
DNYQSCTRLDARNDLIPYRKG	1188–1208	1.0163	5.56	No	Yes	No
CHCKTNCED	1273–1281	1.1907	100.00	Yes	No	Yes
NQKIDLSQL	1327–1335	0.5667	100.00	No	Yes	Yes