Punica granatum L. Leaf Extract Attenuates Lung Inflammation in Mice with Acute Lung Injury

Figure 4

Effects of the pretreatment with EAFPg on TNF-α (a), IL-1β (b), IL-6 (c), and IL-10 gene expression in the lungs of the animals divided into six groups. Animals were randomly distributed into six groups (/group). Mice received in the prophylactic scheme EAFPg (30 mg/kg, 100 mg/kg, and 300 mg/kg, p.o.), dexamethasone (DEXA, 5 mg/kg, p.o.), or vehicle (PBS, p.o.). The values are presented as the median and interquartile range. Significances were calculated by one-way ANOVA followed by the Newman-Keuls multiple comparison test analysis. Groups versus nonpretreated saline-injected mice () and versus nonpretreated LPS-installed mice ().

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