Phenotypic Characterization of Circulating CD4⁺ T Cells in ANCA-Associated Vasculitis

Figure 4

Percentage of Tregs (CD45⁺CD3⁺CD4⁺CD127⁻CD25⁺CD45R0⁺CD194⁺) of the CD4⁺ T cell population in peripheral blood from patients with ANCA-associated vasculitis (AAV), divided into GPA and MPA or PR3-ANCA and MPO-ANCA, healthy blood donors (HBD), and therapy controls (TC). Three statistical analyses were done using the Kruskal-Wallis test followed by Dunn’s multiple comparison test: first, AAV was compared to TC and HBD; second, GPA and MPA were compared to TC and HBD; third, PR3-ANCA and MPO-ANCA were compared to TC and HBD. The only difference found was between MPA patients and TC.