Research Article

Phenotypic Characterization of Circulating CD4+ T Cells in ANCA-Associated Vasculitis

Table 3

Concentrations of CD4+ T cell-related cytokines and chemokines in plasma from patients with ANCA-associated vasculitis (AAV) and healthy blood donors (HBD).

IFN-γCXCL9IL-4CCL22IL-23IL-17ACCL20

AAV 13.6 (12.8, 14.6)61.5 (38.9, 79.7)6.21 (6.21, 7.19)248.1 (171.2, 398.8)53.8 (50.3, 57.3)7.51 (7.10, 8.44)28.6 (21.4, 39.5)
Active AAV 13.6 (12.8, 14.4)60.4 (43.4, 65.0)6,21 (4.43, 7.0)221.4 (34.9, 248.1)52.6 (50.3, 57.3)7.92 (7.10, 8.23)35.8 (28.6, 37.2)
Inactive AAV 13.8 (12.8, 14.8)64.0 (37.0, 80.1)6,66 (6.21, 7.32)258.3 (174.8, 507.2)53.5 (50.3, 57.3)7.46 (7.07, 8.64)21.3 (21.3, 0.434)
GPA 13.2 (12.8, 14.4)51.8 (37.0, 69.1)7.10 (6.21, 7.55)239.9 (190.7, 359.8)53.8 (50.9, 57.3)7.82 (7.20, 8.64)25.3 (18.5, 35.8)
MPA 14.0 (12.9, 16.0)72.5 (56.1, 117.4)6.21 (5.10, 6.43)258.3 (73.3, 647.9)53.8 (50.3, 60.9)7,05 (7.00, 8.15)38.2 (30.5, 74.1)
HBD 12.8 (12.2, 13.2)22.1 (19.5, 30.4)6.21 (6.21, 7.99)252.2 (180.4, 307.5)53.8 (50.3, 56.1)7.72 (7.20, 8.18)16.2 (15.0, 18.1)

Concentrations are measured in pg/mL. Figures represent median with interquartile ranges. and , when compared with HBD.