Role of Exercise in Vascular Function and Inflammatory Profile in Age-Related Obesity

Table 1

Subjects characteristics and between groups comparison.

	NW ()	OW&OB ()
Age (years)	70.3 ± 4.7	69.4 ± 5.4	ns
Female/male ()	16/14	23/17	ns
BMI (kg ∙ (m^2)^−1)	23.9 ± 2.6	30.1 ± 2.3
Sys (mmHg)	133.1 ± 14.7	147.5 ± 16.2
Dia (mmHg)	76.7 ± 7.6	83.9 ± 10.4
Medications
Statin— (%)	7 (23)	10 (25)	ns
Diuretics— (%)	5 (17)	7 (18)	ns
Antiacid— (%)	5 (17)	6 (15)	ns
Physical activity
Years	5 ± 1	5 ± 2	ns
Min/week	209.4 ± 82.5	221.7 ± 71.3	ns
Days/week	3 ± 1	3 ± 1	ns
6MWT (m)	610.1 ± 68.5	610.0 ± 83.7	ns
Inflammatory profile
IL-10 (ng/mL)	18.9 ± 22.6	16.6 ± 17.2	ns
IL-1ra (ng/mL)	61.9 ± 33.6	52.7 ± 24.1	ns
IL-1β (ng/mL)	9.1 ± 7.2	7.8 ± 5.1	ns
IL-8 (ng/mL)	5.9 ± 4.4	7.1 ± 4.1	ns

Plus-minus values are means ± standard deviation (SD). One-way ANOVA was used to identify between-group differences for parametric variables, followed by the Holm-Sidak test. The Kruskal-Wallis one-way analysis of variance on ranks was used for nonparametric variables, followed by the Tukey test. Note: NW: normal weight; OW&OB: overweight and obese; BMI: body mass index, activity (min/week); Sys: systolic blood pressure; Dia: diastolic blood pressure; FMD: flow-mediated dilation; 6MWT: 6-minute walking test; CRP: C-reactive protein; IL: interleukin; MCP-1: monocyte chemoattractant protein-1; TNF-α: tumor necrosis factor-α; .