Three Types of Broadly Reacting Antibodies against Influenza B Viruses Induced by Vaccination with Seasonal Influenza Viruses

Figure 8

Competitive ELISA among isolated clones. The binding activity of Fab-PP Ab (indicated at the top) to B/Massachusetts/2/2012 virus particles was measured by ELISA in the presence of a 10-fold greater concentration of Fab-cp3 Ab (indicated at the left). F008-009, which is not an anti-HA Ab, was used as a control. The binding activity of Fab-PP in the presence of Fab-cp3 Ab was indicated as relative values as follows: the absorbance value in the presence of F008-009cp3 was set as 100% binding and the binding activity in the presence of various Fab-cp3 forms of Abs is indicated as % values.