Research Article
NF-κB-94ins/del ATTG Genotype Contributes to the Susceptibility and Imbalanced Th17 Cells in Patients with Immune Thrombocytopenia
Table 4
The results of NF-κB-94ins/del and clinical characteristics.
| | Genotypes | Allelic frequency | | WW | WD | DD | Allele W | Allele D |
| | Gender | | | | | | | Male | 62 (40%) | 56 (36.13%) | 37 (23.87%) | 180 (58.06%) | 130 (41.94%) | | Female | 117 (47.18%) | 90 (36.29%) | 41 (16.53%) | 324 (65.32%) | 172 (34.68%) | | | | 0.282 | 0.037 | | 0.038 | | Stage | | | | | | | nITP | 95 (46.8%) | 72 (35.47%) | 36 (17.73%) | 262 (64.53%) | 144 (35.47%) | | pITP | 27 (44.26%) | 20 (32.79%) | 14 (22.95%) | 74 (60.66%) | 48 (39.34%) | | cITP | 57 (41.91%) | 52 (38.24%) | 27 (19.85%) | 166 (61.03%) | 106 (38.97%) | | rITP | 0 | 2 | 1 | 2 | 4 | | | | 0.396 | 0.379 | | 0.351 | | Severity | | | | | | | sITP | 76 (42.94%) | 59 (33.33%) | 42 (23.73%) | 211 (59.60%) | 143 (40.40%) | | nsITP | 103 (45.58%) | 87 (38.50%) | 36 (15.93%) | 293 (64.82%) | 159 (35.18%) | | | | 0.398 | 0.061 | | 0.129 | | Response | | | | | | | CR + R | 149 (43.44%) | 122 (35.57%) | 72 (20.99%) | 420 (94.17%) | 26 (5.83%) | | NR | 30 (50.00%) | 24 (40.00%) | 6 (10.00%) | 84 (70.00%) | 36 (30.00%) | | | | 0.938 | 0.054 | | 0.067 | | MAIPA | | | | | | | Positive | 26 (37.68%) | 25 (36.23%) | 18 (26.09%) | 77 (55.80%) | 61 (44.20%) | | Negative | 37 (46.84%) | 23 (29.11%) | 19 (24.05%) | 97 (59.88%) | 65 (40.12%) | | | | 0.257 | 0.473 | | 0.476 |
|
|
