Sevoflurane Inhibits the Th2 Response and NLRP3 Expression in Murine Allergic Airway Inflammation

Figure 6

Effect of sevoflurane and MCC950 on NLRP3, ASC, pro-caspase-1 and caspase-1 expression in lung tissue. (a) Western blot analysis of NLRP3, ASC, pro-caspase-1, caspase-1 and actin expression in lung tissue. (b–e) Relative levels of NLRP3, ASC, pro-caspase-1 and caspase-1 expression in lung tissue. (f, g) Production of IL-18 and IL-1β in the BALF. Data are expressed as the mean ± SEM of six mice per group from three separate experiments, .

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