Hsa_circ_0001859 Regulates ATF2 Expression by Functioning as an MiR-204/211 Sponge in Human Rheumatoid Arthritis

Figure 6

RA-related molecular signaling pathway. ATF2 is involved in the TLR signaling and TNF pathways. ATF2 regulates transcriptions with the c-Fos protein to regulate the expression of GMCSF, CCL5, IL-6, and IL-1b. Hsa_circ_0001859 can also regulate ATF2 by inhibiting miR-204/211.