Journal of Immunology Research / 2018 / Article / Tab 5

Research Article

Immune Response to Rotavirus and Gluten Sensitivity

Table 5

Genes modulated in the three datasets playing a role in selected GO BPs related to the viral infection process.

Gene symbolGene titleFC

NCGS dataset
Viral transcription/gene expression
  RANBP2RAN-binding protein 21.98
  RPL27ARibosomal protein L27a3.22
  RPL37ARibosomal protein L37a2.94
  RPLP2Ribosomal protein, large, P22.15
  RPS10Ribosomal protein S102.66
  RPS11Ribosomal protein S112.49
  TPRTranslocated promoter region, nuclear basket protein4.40
Response to virus
  RELAv-rel reticuloendotheliosis viral oncogene homolog A (avian)1.54
  IKBKBInhibitor of kappa light polypeptide gene enhancer in B cells, kinase beta2.69
  IRF5Interferon regulatory factor 51.52
  IFNA17Interferon, alpha 171.59
  DDX3XDEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked3.22
  STAT2Signal transducer and activator of transcription 2, 113 kDa1.59
  STAT1Signal transducer and activator of transcription 1, 91 kDa2.73
  IRF3Interferon regulatory factor 31.67
  DDX17DEAD (Asp-Glu-Ala-Asp) box helicase 174.75
Viral life cycle
  TPRTranslocated promoter region, nuclear basket protein4.40
  ATG16L1Autophagy-related 16-like 1 (S. cerevisiae)1.87
  HSP90AB1Heat shock protein 90 kDa alpha (cytosolic), class B member 11.87
  RANBP2RAN-binding protein 21.98
  DPP4Dipeptidyl-peptidase 41.61
  DDX6DEAD (Asp-Glu-Ala-Asp) box helicase 64.70
  HTATSF1HIV-1 Tat specific factor 12.23
  SLAMF1Signaling lymphocytic activation molecule family member 11.65
  T84 dataset
Viral transcription/gene expression
  RPL27ARibosomal protein L27a1.68
  RPS2Ribosomal protein S21.99
  RPS6Ribosomal protein S61.51
Response to virus
  IFIH1Interferon induced with helicase C domain 11.52
  IFNA7Interferon, alpha 71.53
  IFIT3Interferon-induced protein with tetratricopeptide repeats 31.46
  IFNA4Interferon, alpha 41.73
  IFI44Interferon-induced protein 441.46
  IFNGR1Interferon gamma receptor 11.67
  IFNA17Interferon, alpha 171.56
Viral life cycle
  CTBP1C-terminal-binding protein 11.58
  ADRBK1Adrenergic, beta, receptor kinase 11.46
  HCRP1Hepatocellular carcinoma-related HCRP11.61
  C9Orf28Chromosome 9 open reading frame 281.56
Rotavirus infection dataset
Viral transcription/gene expression
  NUP58Nucleoporin 58 kDa6.38
  RPS16Ribosomal protein S162.10
  DENRDensity-regulated protein2.11
Response to virus
  XPR1Xenotropic and polytropic retrovirus receptor 11.72
  CNOT7CCR4-NOT transcription complex subunit 73.54
  CD40CD40 molecule, TNF receptor superfamily member 52.72
  ITCHItchy E3 ubiquitin protein ligase2.26
  ARF1ADP-ribosylation factor 11.91
  BCL2L11BCL2-like 11 (apoptosis facilitator)3.21
  BCL2L1BCL2-like 13.37
  IKBKEInhibitor of kappa light polypeptide gene enhancer in B cells, kinase ɛ1.50
  DDX17DEAD (Asp-Glu-Ala-Asp) box helicase 172.13
Viral life cycle
  NUP153Nucleoporin 153 kDa2.01
  VPS37AVacuolar protein sorting 37 homolog A (S. cerevisiae)1.90
  XPR1Xenotropic and polytropic retrovirus receptor 11.72
  UBBUbiquitin B1.75
  ITCHItchy E3 ubiquitin protein ligase2.26
  NUP58Nucleoporin 58 kDa6.38
  TNFRSF4Tumor necrosis factor receptor superfamily, member 41.94
  SCARB2Scavenger receptor class B, member 21.96