|
| Gene symbol | Gene title | FC |
|
| Immune response |
| ADGRE3 | Adhesion G protein-coupled receptor E3;ADGRE3;ortholog | −3.35 |
| ADIPOQ | Adiponectin, C1Q and collagen domain containing | −1.60 |
| BLK | BLK proto-oncogene, Src family tyrosine kinase | 1.72 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | 1.57 |
| BTK | Bruton agammaglobulinemia tyrosine kinase | −1.59 |
| C1QTNF9 | C1q and tumor necrosis factor related protein 9 | −1.69 |
| CD109 | CD109 molecule | −1.84 |
| CD79B | CD79b molecule, immunoglobulin-associated beta | −1.67 |
| CLEC7A | C-type lectin domain family 7, member A | −1.62 |
| CMIP | c-Maf inducing protein | −3.50 |
| CSF2RA | Colony-stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) | −2.30 |
| CXCL2 | Chemokine (C-X-C motif) ligand 2 | −3.76 |
| CXCL8 | Chemokine (C-X-C motif) ligand 8 | −8.65 |
| FCER1A | Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide | −5.64 |
| HCST | Hematopoietic cell signal transducer | 1.85 |
| IL18BP | Interleukin 18 binding protein | 1.56 |
| JAG1 | Jagged 1 | −2.06 |
| KLRB1 | Killer cell lectin-like receptor subfamily B, member 1 | −5.99 |
| MAP3K11 | Mitogen-activated protein kinase kinase kinase 11 | 1.55 |
| MASP1 | Mannan-binding lectin serine peptidase 1 | −1.50 |
| MR1 | Major histocompatibility complex, class I-related | 8.43 |
| PLEKHN1 | Pleckstrin homology domain containing, family N member 1 | −1.99 |
| PPP2R2C | Protein phosphatase 2, regulatory subunit B, gamma | −1.84 |
| PPP3CA | Protein phosphatase 3, catalytic subunit, alpha isozyme | −1.89 |
| PSME3 | Proteasome activator subunit 3 | 1.91 |
| PVR | Poliovirus receptor | −1.59 |
| STAT5B | Signal transducer and activator of transcription 5B | −2.06 |
| TNFRSF10C | Tumor necrosis factor receptor superfamily, member 10c decoy without an intracellular domain | −1.75 |
| TNFRSF4 | Tumor necrosis factor receptor superfamily, member 4 | 1.94 |
| Type I interferon signaling |
| Positive regulation of Type I interferon production | |
| EP300 | E1A-binding protein p300 | −1.56 |
| POLR3G | Polymerase (RNA) III (DNA directed) polypeptide G (32kD) | −1.98 |
| CREBBP | CREB-binding protein | −1.83 |
| LRRFIP1 | Leucine rich repeat (in FLII) interacting protein 1 | −2.14 |
| SOCS1 | Suppressor of cytokine signaling 1 | 2.32 |
| Negative regulation of Type I interferon production | |
| UBB | Ubiquitin B | 1.75 |
| ITCH | Itchy E3 ubiquitin protein ligase | 2.26 |
| TAX1BP1 | Tax1 (human T cell leukemia virus type I) binding protein 1 | −4.01 |
| Negative regulation of Type I interferon pathway | |
| PTPN2 | Protein tyrosine phosphatase, nonreceptor type 2 | 2.10 |
| Positive regulation of interferon beta production | |
| ZBTB20 | Zinc finger and BTB domain containing 20 | 4.27 |
| Negative regulation of interferon Beta production | |
| PTPRS | Protein tyrosine phosphatase, receptor type, S | −2.00 |
| CACTIN | Cactin, spliceosome C complex subunit | −2.53 |
| Cellular response to interferon alpha | |
| TPR | Translocated promoter region, nuclear basket protein | −2.55 |
| Negative regulation of interferon alpha production | |
| PTPRS | Protein tyrosine phosphatase, receptor type, S | −2.00 |
| Type I interferon signaling pathway | |
| JAK1 | Janus kinase 1 | 1.79 |
| IFI27 | Interferon, alpha-inducible protein 27 | 75.26 |
| IFI27L2 | Interferon, alpha-inducible protein 27-like 2 | −1.59 |
| IKBKE | Inhibitor of kappa light polypeptide gene enhancer in B cells, kinase epsilon | 1.50 |
| TPR | Translocated promoter region, nuclear basket protein | −2.55 |
| Positive regulation of Type I interferon pathway | |
| MME | Membrane metallo-endopeptidase | −5.54 |
| Gamma interferon signaling |
| JAK1 | Janus kinase 1 | 1.79 |
| HLADQB1 | Major histocompatibility complex, class II, DQ beta 1 | −36.43 |
| HLADQA1 | Major histocompatibility complex, class II, DQ alpha 1 | −37.95 |
| PIAS3 | Protein inhibitor of activated STAT 3 | 2.11 |
| HLADRB1 | Major histocompatibility complex, class II, DR beta 1 | −10.91 |
| MAPK8 | Mitogen-activated protein kinase 8 | −2.28 |
| MAPK1 | Mitogen-activated protein kinase 1 | −2.23 |
| Regulation of interferon gamma signaling pathway | |
| PTPN2 | Protein tyrosine phosphatase, nonreceptor type 2 | 2.10 |
| Positive regulation of interferon gamma production | |
| PDE4B | Phosphodiesterase 4B, cAMP-specific | −1.77 |
| ZFPM1 | Zinc finger protein, FOG family member 1 | 1.75 |
| Negative regulation of interferon gamma production | |
| HLADRB1 | Major histocompatibility complex, class II, DR beta 1 | −10.91 |
| RARA | Retinoic acid receptor, alpha | −7.60 |
| FOXP3 | Forkhead box P3 | −2.14 |
| Cellular response to interferon gamma | |
| SLC26A6 | Solute carrier family 26 (anion exchanger), member 6 | 1.95 |
| DAPK3 | Death-associated protein kinase 3 | −1.62 |
| CD40 | CD40 molecule, TNF receptor superfamily member 5 | 2.72 |
| MEFV | Mediterranean fever | −4.83 |
| SNCA | Synuclein alpha | 8.62 |
| MRC1 | Mannose receptor, C type 1 | −1.93 |
| Toll-like receptors signaling pathway |
| TANK | TRAF family member-associated NFKB activator | −1.91 |
| NFKBIA | Nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha | −1.76 |
| MAPK8 | Mitogen-activated protein kinase 8 | −2.28 |
| IKBKE | Inhibitor of kappa light polypeptide gene enhancer in B cells, kinase epsilon | 1.50 |
| MAPK1 | Mitogen-activated protein kinase 1 | −2.23 |
| JUN | jun proto-oncogene | −1.91 |
|
