PD-L1 Expression Predicts a Distinct Prognosis in Krukenberg Tumor with Corresponding Origins
Table 1
Univariate and multivariate analysis for prognostic factors affecting OS in GC.
Risk factors
Univariate analysis
Risk factors
Multivariate analysis
HR (95% CI)
HR (95% CI)
Menopause status: menopause
2.860 (1.057–7.736)
0.038
Menopause status: menopause
2.609 (0.848–8.033)
0.095
Tumor PD-L1 expression: positive
3.201 (1.273–8.050)
0.013
Tumor PD-L1 expression: positive
2.413 (0.905–6.437)
0.078
CD3+ cell density: high
1.132 (0.475–2.701)
0.779
CD8+ cell density: low
2.003 (0.776–5.171)
0.151
CD8+ cell density: low
1.774 (0.709–4.438)
0.220
FOXP3+ cell density: high
0.964 (0.405–2.294)
0.934
PD1+ cell density: high
0.856 (0.363–2.021)
0.723
Primary tumor size: ≥5 cm
1.956 (0.791–4.840)
0.147
Lymph node invasion: positive
1.735 (0.385–7.811)
0.473
Vascular invasion: positive
1.393 (0.576–3.365)
0.462
Neural invasion: invasion
1.271 (0.535–3.016)
0.587
Ovarian involvement: bilateral
1.926 (0.699–5.305)
0.205
Tumor PD-L1 expression, CD3+ cell density, CD8+ cell density, FOXP3+ cell density, and PD1+ cell density are evaluated in KTs, and variables showing values less than 0.05 are presented in italic.
